Meryl Streep Miranda Priestly Anne Hathaway Andy Sachs Emily Blunt Emily Stanley Tucci Nigel Simon Baker Christian Thompson Adrian Grenier Nate Tracie Thoms Lily Rich Sommer Doug Daniel Sunjata James Holt David Marshall Grant Richard Sachs James Naughton Stephen Tibor Feldman Irv Ravitz Rebecca Mader Jocelyn Jimena Hoyos Lucia Gisele Bündchen Serena George C. Wolfe Paul John Rothman Editor Stephanie Szostak Jacqueline Follet Colleen Dengel Caroline Suzanne Dengel Cassidy Heidi Klum Heidi Klum Bridget Hall Bridget Hall Ines Rivero Clacker in Elevator Alyssa Sutherland Clacker Robert Verdi Fashion Reporter Paul Keany St. Regis Butler David Callegati Massimo James Cronin Ambassador Eric Seltzer Roy Lindsay Brice PR Woman Ilona Alexandra Red Carpet Celebrity (uncredited) Frank Anello Security (uncredited) Alexander Blaise French Bellhop (uncredited) Carl Burrows Businessman (uncredited) Guy A. Fortt Security (uncredited) Alexie Gilmore Clacker (uncredited) Toree Hill Guest (uncredited) Tim Krueger Fund Raiser (uncredited) Hector Lincoln Hector Lincoln (uncredited) Nina Lisandrello Clacker (uncredited) Matt Murray Paparazzo (uncredited) Ingrid Sophie Schram Clacker (uncredited) Brandhyze Stanley Waitress (uncredited) Jen Taylor Lou - Dowager (uncredited) Taylor Treadwell Miranda's New Assistant (uncredited) Donatella Versace Donatella Versace (uncredited)