George Clooney Frank Walker Hugh Laurie David Nix Britt Robertson Casey Newton Raffey Cassidy Athena Tim McGraw Eddie Newton Chris Bauer Frank's Dad Shiloh Nelson Young Casey Newton Kathryn Hahn Ursula Keegan-Michael Key Hugo Thomas Robinson Young Frank Walker Pierce Gagnon Nate Newton Matthew MacCaull Dave Clark Judy Greer Jenny Newton Matthew Kevin Anderson Bus Driver Michael Giacchino Small World Operator D. Harlan Cutshall Skyscraper Foreman Xantha Radley History Teacher David Nykl Science Teacher Paul McGillion English Teacher Garry Chalk Jail Desk Jockey Dagan Nish Jail Punk Alex Barima Jetpack Buddy Jedidiah Goodacre Jetpack Buddy Kate Crutchlow Monorail Mother Priya Rajaratnam Young Astronaut Parm Soor Astronaut's Father Leena Manro Astronaut's Mother Rick Pearce Pickup Driver Tom Butler Police Captain Tim Perez Deputy Patrick Sabongui Eiffel Tower Guard #1 Darren Shahlavi Tough Guard Amy Esterle Greyhound Girl (uncredited) Monique Ganderton Dave Clark #1 (uncredited) Kory Grim Dave Clark Henchman (uncredited) Raiden Integra Pedestrian (uncredited) Jaeda Lily Miller Young Casey (uncredited) Lochlyn Munro Uncle Anthony (uncredited)